Carcinoid Heart Disease

Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.

Also Known As:

Carcinoid Heart Diseases; Heart Disease, Carcinoid; Heart Diseases, Carcinoid

Neoplasms: 1324753
- Neoplasms by Histologic Type: 2
  - Germ Cell and Embryonal Neoplasms: 4454
    - Neuroectodermal Tumors: 217
      - Neuroendocrine Tumors: 6270
        Carcinoid Tumor: 5501
        Malignant Carcinoid Syndrome: 50
        Carcinoid Heart Disease: 148
  - Glandular and Epithelial Neoplasms: 439
    - Carcinoma: 141855
      - Adenocarcinoma: 58365
        Carcinoid Tumor: 5501
        Malignant Carcinoid Syndrome: 50
        Carcinoid Heart Disease: 148
  - Nerve Tissue Neoplasms: 1
    - Neuroectodermal Tumors: 217
      - Neuroendocrine Tumors: 6270
        Carcinoid Tumor: 5501
        Malignant Carcinoid Syndrome: 50
        Carcinoid Heart Disease: 148
Cardiovascular Diseases: 91362
- Heart Diseases: 26014
  - Carcinoid Heart Disease: 148

Cornelis A de Groot Selected Research

Cornelis A de Groot Research Topics

Disease

Drug/Important Bio-Agent (IBA)